生物医药----蛋白质相互作用

张高

 

一、基于纳米粒子技术的蛋白质纯化与识别系统

We have built a novel system to immobilize and recover DNA-binding protein (HMGB1/2), without being interfered by non-specific proteins bound on the beads surface. This method should be widely applicable to purify weakly but specific binding proteins toward DNA or DNA-protein complexes

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

二、阿尔茨海默氏病β淀粉样沉淀蛋白的分子间相互作用及数量化检测

 Interaction between proteins on QCM sensor：

 

 

Ab aggregation analysis by QCM：

三、PPAR gamma基因与骨关节炎、风湿性关节炎及年龄的关系：